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Other post-translational modifications include glycosylation of the N-terminal glycopeptide (44), C-terminal amidation of N-terminal glycopeptide, joining peptide and alpha-MSH (45,46), and N-terminal acetylation of ACTH, alpha-MSH and beta-endorphin (47,48)

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In contrast, ANGPT-2 has been shown to induce vessel destabilization, pericytes detachment, vessel sprouting and angiogenesis [147]