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Two reactions involving glucose metabolites catalyse the reduction of NADP+ to NADPH: glucose 6-phosphate dehydrogenase, forming 6-phosphogluconate, and phosphogluconate dehydrogenase, which yields the 5-carbon sugar ribulose 5-phosphate, liberating carbon dioxide from carbon-1 of the substrate

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The transcription factor p53 is well-known to control cellular fate by dictating major stress-related pathways like apoptosis 31

Post-Reconstitution: Once mixed with a solvent, store immediately at 2-8C and use promptly