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These effects make it especially relevant for conditions involving irritation or breakdown of the intestinal barrier

Patel R, Terasaki PI

The benzyl alcohol preservative has been linked to severe toxicity in this population, including a potentially fatal condition known as gasping syndrome. Newborns have immature metabolic pathways and cannot efficiently metabolize benzyl alcohol, leading to its accumulation and metabolic acidosis with respiratory failure in severe cases

Patients on MAOIs, stimulant medications for ADHD, or decongestants containing phenylephrine face amplified sympathetic overdrive when phentermine is introduced