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In the treatment of breast cancer, anti-estrogen tamoxifen, the drug most often used for the long-term treatment of early breast cancer, can induce apoptosis in many cells, and this effect may be mediated by ROS generation in the mitochondria of breast cancer cells [71]

Several human and preclinical studies emphasize the importance of gut microbiome during the first 1,000 days of life, both maternal and infant, in shaping immune development in childhood (74)

After embryo culture, the rates of blastocyst development from cleaved two-cell embryos in each group were microscopically observed and calculated as the percentage of blastocysts/cleaved two-cell embryos