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3.2.1 Hormonal abnormalities in the HPT axis The hypothalamus-pituitary-thyroid axis (HPT) is a hormone axis that regulates thyroid function by grading and feedback regulation of thyrotropin-releasing hormone (TRH), thyrotropin (TSH), thyroxine (T4), and triiodothyronine (T3)

While GSSG has its own biological roles, it is not the reduced, active form (GSH) that researchers are typically studying

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These include redness, swelling, tenderness, itching, bruising, and occasionally a small lump or bump under the skin that may persist for several days