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Importantly, serum B12 levels can be misleadingly normal or even elevated in chronic liver disease due to increased levels of binding proteins (such as haptocorrin) and reduced clearance, meaning that total B12 measurements may not accurately reflect tissue B12 status or functional deficiency

A: Viewing fat loss as the outcome of nutrition and activity is safer

A 2016 study published in Nature Medicine demonstrated that MOTS-c administration improved insulin sensitivity and reduced diet-induced obesity in mouse models, even when started after metabolic dysfunction was already established

Some antibiotics may not be absorbed as well when taking B12 externally