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Traditional treatments, such as rest, anti-inflammatory medications, or cortisone shots, may provide only temporary relief
Miscellaneous Extraintestinal Manifestations and Complications of Inflammatory Bowel Disease Renal Nephrolithiasis (oxalate, urate) Glomerulonephritis (rare) Right ureteral obstruction Urinary system fistulas (eg, enterovesical, colovesical, rectourethral) Tubulointerstitial nephritis (5-aminosalicylates) Secondary amyloidosis Hematologic Anemia Iron deficiency Vitamin B12 deficiency Folic acid deficiency Anemia of chronic disease Autoimmune hemolytic anemia Neoplastic Myelodysplastic syndrome (rare) Promyelocytic leukemia (rare) Cardiopulmonary Pericarditis (extraintestinal manifestation or drug-induced) Myocarditis Conduction abnormalities Pneumonitis Eosinophilic pneumonia Cryptogenic organizing pneumonia Bronchiectasis, bronchiolitis, bronchitis, and subglottic stenosis Pancreatic Acute pancreatitis Drug-induced (purine analogues,5-aminosalicylates) Duodenal Crohn disease Granulomatous involvement of pancreas (rare) Chronic pancreatitis Autoimmune pancreatitis Thrombophilia Multifactorial Nephrolithiasis is a recognized problem for patients with CD, particularly ileal CD
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The damage typically affects the longest nerves first, producing the classic stocking-and-glove distribution of numbness and pain in feet and hands
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