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[PMC free article: PMC5047290] [PubMed: 26361259] 235

The reaction mixture consisted of 50 L of enzyme extract, 1.75 mL of 50 mM sodium phosphate buffer (pH 7.0), and 0.1 mL of 4% guaiacol

PMID: 47 HurrellBPSakanoYShenSHelouDGLiMShafiei-JahaniPet al

JHU083 has also demonstrated excellent therapeutic efficacy in preclinical models of IDH-mutant gliomas and significantly reduces mTOR signaling (Yamashita et al., 2021)