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Injection Administration: The injection is administered intramuscularly, typically in the arm, thigh, or buttocks

In contrast, the passive diffusion process of B 12 absorption normally a very small portion of total absorption of the vitamin from food consumption may exceed the haptocorrin- and IF-mediated absorption when oral doses of B 12 are very large, with roughly 1% efficiency

It binds to transport proteins, primarily transcobalamin II , which delivers B12 to tissues throughout the body

People with chronic health conditions, gastrointestinal absorption issues, and pregnant women tend to benefit most from injections