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Iantomasi, T., Favilli, F., Marraccini, P., Magaldi, T., Bruni, P., & Vincenzini, M

"GLP-1s are the first in class, but that doesnt make them the best in class." Amylin analogs in a GLP-1 world Semaglutide, the main molecule in Novo Nordisks popular Ozempic and Wegovy, acts like the GLP-1 hormone secreted by the intestine

Furthermore, monocyte-derived macrophages are among the first, and most abundant, immune cells to traffic into the islet in both murine models and human patients (11, 63), and it is hypothesized that this initial influx is induced by increased levels of CCL2