The exact dose depends on the patients B12 levels, any health issues, and how well they respond to treatment
No specific interactions have been documented that make these combinations dangerous
Conversely, some studies show that a deficiency in vitamin B12 may cause appetite loss, potentially leading to weight loss if left untreated ( If youre low or deficient in B12, your healthcare provider will likely recommend oral vitamin B12 supplements or injections to increase your blood levels ( summary Low levels of vitamin B12 can cause megaloblastic anemia, which is characterized by shortness of breath, headaches, and fatigue
Conversely, medications that further slow gastric emptying, such as anticholinergics or opioid analgesics, may exacerbate gastrointestinal adverse effects including nausea, vomiting, and constipation