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Several folate transporters have been identified and characterized: the reduced folate carrier, the folate receptors, and the proton-coupled folate transporter 881

doi: 10.1111/obr.12863

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There is also variable contribution from T-helper type 1 (Th1) driven pathways, including interferon-gamma (IFN-) and interleukin 12 (IL-12), as well as T-helper type 17 (Th17) and T-helper type 22 (Th22) cells [25]