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Mild and short-lived side effects can include injection-site redness, transient lightheadedness and very rarely mild nausea

However, the pharmacokinetic parameters after repeated IM administration changed slightly compared to those observed after a single IM injection, with a small decrease in C max and t 1/2 and an increase in T max

While promising in research for fat metabolism and potentially cartilage repair, large trials showed good efficacy with AOD9604 for obesity, but it remains a research tool for studying fat burning and metabolic pathways, often used off-label in wellness settings alongside diet and exercise with promising affects for cartilage repair

Both the RNA and protein levels were determined by RT/real-time PCR (Figure 1A,B) and Western blotting (Figure 1C,D), respectively