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Several studies have found that intestinal permeability is higher in patients with celiac disease ( In fact, one study found that ingesting gluten significantly increases intestinal permeability in celiac patients immediately after consumption ( Diabetes There is some evidence that increased intestinal permeability plays a role in the development of type 1 diabetes ( Type 1 diabetes is caused by an autoimmune destruction of insulin-producing beta cells in the pancreas ( It has been suggested that the immune reaction responsible for beta cell destruction may be triggered by foreign substances leaking through the gut ( One study found that 42% of individuals with type 1 diabetes had significantly elevated zonulin levels

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