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The pipeline confirms the company is not standing still: the REDEFINE 1 Phase 3 trial of CagriSema a fixed-ratio combination of semaglutide and the amylin analogue cagrilintide demonstrated 22.7% weight loss at 68 weeks, superior to semaglutide alone

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Reported activities include fibroblast stimulation, controlled intracellular copper delivery, modulation of collagen and glycosaminoglycan synthesis, and broad changes in gene expression across stress-response and tissue-repair networks