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This step also creates a smoother smoke once the leaves have been rolled into the cigar

For example, industry documents show that Newport employees handing out samples in predominantly Black communities from a Newport van were instructed to assertively ask people to accept samples of Newports as part of an overall effort to provide aggressive promotional and advertising support for the brand. A 1981 RJ Reynolds corporate document stated that the Black segment has been identified as the Brands Special Market priority for its Salem brand

Statistical analysis For baseline characteristics, continuous variables were summarized using mean and standard deviation or median and interquartile range

Nonetheless, longitudinal studies are needed to confirm temporal sequencing and to rule out residual confounding