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Early Clinical Development Initial clinical studies focused on evaluating safety, tolerability, pharmacokinetics, and biological activity

Wehkamp J, Harder J, Wehkamp K, Wehkamp-von Meissner B, Schlee M, Enders C, Sonnenborn U, Nuding S, Bengmark S, Fellermann K, Schrder JM, Stange EF: NF-B- and AP-1-mediated induction of human -defensin-2 in intestinal epithelial cells by Escherichia coli Nissle 1917: a novel effect of a probiotic bacterium

She earned her Midwifery degree from the University of Greenwich in 2007, giving her a solid foundation in patient care and safety, values she upholds in her aesthetic practice

They do not have any significant side effects