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Given that implanted chondrocytes are responsible for the generation of new cartilage in the defect site, it is not surprising that the quality of these cells critically aects the reparative results of ACI treatment (Davies and Kuiper, 2019)

Exploratory efficacy criteria included scales for which no significant benefit was expected, but which were worth examining in preparation for the next clinical trial: on actimetry, the bradykinesia score (50th percentile: normal value = 18.6)

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