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Kidney metabolomic analysis revealed that FVP treatment inhibited ferroptosis by increasing glutathione (GSH), glutathione peroxidase 4 (GPX4), and solute carrier family 7 member 11 (SLC7A11) expression while reducing AA accumulation ( Figure 5 ) [192]

In 1982, the basic defect in cystinosis was elucidated as deficient or absent transport of cystine out of lysosomes [4]

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Other potential pathways may also be involved in the protective action of taurine against hyperglycemia-induced endothelial dysfunction