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Acute myeloid leukemia creates an arginase-dependent immunosuppressive microenvironment

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Research has found that exposing renal tubular epithelial cells to various concentrations of CaOx crystal solution results in a significant increase in the expression of ferroptosis-related proteins such as p53, ACSL4, transferrin receptor (TRC), and TF as the concentration of CaOx crystals increases

These aforementioned points, with or without therapy, would have a NO background