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11 Furthermore, novel bile acids produced by microbial metabolism, such as tauro--muricholic acid, have been found to indirectly regulate hepatic lipid metabolism and inflammation by antagonizing intestinal FXR, providing new targets for interventions based on the microbe-bile acid axis

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Size, Surface Functionalization, and Genotoxicity of Gold Nanoparticles In Vitro

Of note, 65% (701 genes) of genes with significant DoTT (5-fold change in 4sU-seq signal downstream/upstream of PAS) in ICP27-expressing cells also displayed similar defect in HSV-1-infected cells (Fig