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The spray is imaged using high-speed photography or laser-sheet imaging, and the image is analyzed for: D max (the longest diameter of the spray cross-section), Dmin (the shortest diameter), and the ovality ratio (D max /D min ) a measure of how circular the spray is

A direct consequence of this is that the difference in efficacy between retatrutide and tirzepatide (approximately -7,8 points) must be weighed against this difference in tolerability and a discontinuation rate two to three times higher

a Standard controls used in the assay based on permeability classifications BLQ: No peak detected in receiver side sample for A B transport NC: not calculable 3.2

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