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Figure 1 Structure and function of SLC7A11 System Xc- is composed of two subunits: the light chain functional subunit SLC7A11, also referred to as xCT, and the heavy chain structural subunit SLC3A2, also known as CD98 or 4F2hc ( In humans, the gene encoding SLC7A11 is situated on chromosome 4 and comprises 14 exons, resulting in a protein sequence of 502 amino acids

A case of histopathologically typical toxic epidermal necrolysis despite no visible blisters or erosive lesions

Increased expression of senescence-associated cell cycle inhibitor p16INK4a in deteriorating renal transplants and diseased native kidney

One study found that the most effective way to treat patients with this liver illness was to provide large intravenous doses of glutathione