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Br J Pharmacol 119(8):15331540 Mehta R, Pascual M, Soroko S, Savage B, Himmelfarb J, Ikizler T, Paganini E, Chertow G (2004) Spectrum of acute renal failure in the intensive care unit: the PICARD experience

Furthermore, clinical trials have demonstrated that GnRH-a reduces ER and PR expression in a dose-dependent manner and suppresses vascular endothelial cell proliferation, thereby reducing fibroid growth [152]

As a naturally occurring antioxidant synthesized within the body, glutathione can mitigate oxidative stress, bolster the immune system, and improve insulin sensitivity

The rational to target PD-1/PD-L1 axis in senescence is evident and the large panel of drugs approved to target this pathway will probably accelerate the development of this strategy