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The AAD recommend the following medical options for reducing scars: steroid injections, which may ease pain and reduce the size of keloid and other scars laser treatments, which can reduce redness, pain, and hardness of keloid and other scars

Clinically, reserpine is primarily of historical importance , although it is available for use in patients with resistant hypertension, and has been used for many years in animal experiments to deplete catecholamine levels

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In coronary arteries, decreased reactivity to endogenous NO and decreased production of endogenous NO itself have also been noted in smokers [56]