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April 22 Product: Abeona Therapeutics prademagene zamikeracel Indication: Recessive dystrophic epidermolysis bullosa Chemistry, manufacturing and controls (CMC) issues led the FDA to reject Abeona Therapeutics investigational gene-corrected cell therapy prademagene zamikeracel (pz-cel) in recessive dystrophic epidermolysis bullosa, a rare disorder that causes painful blistering and erosion of the skin