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Immunofluorescence staining HFF-1 cells (1.5 10 5 cells per well) or mouse embryonic fibroblasts (NIH3T3) were grown on sterile cell slides for 24 h till 80% confluence

Human data: No human clinical trials have been conducted or published

Increased incidences of early resorptions, ossification delays, and developmental variations, as well as decreased fetal body weights were observed in rats in the presence of maternal toxicity, at systemic exposures (AUC) approximately 10 times higher than exposure at the approved human dose of PAXLOVID

Pyroglutamate may be a promising therapeutic candidate for cognitive dysfunction in schizophrenia and other conditions with glutathione disturbances