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The observed immunopathology was associated with Th2-cell-biased responses 55 and was largely against the nucleocapsid protein 56,58

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Studies on human skin fibroblasts (Moeller et al.) have demonstrated T3 activating effect on numerous enzymes of the glycolysis pathway, as well as: an increase in mRNA for the hypoxia-inducible transcription factor 1-alpha (HIF-1) a key factor in the regulation of glycolysis, an increase in mRNA for the Glucose Transporter Type 1 (GLUT1) transporter, and an increase in mRNA for the Solute Carrier Family 16 Member 3 (SLC16A3) lactate exporter [23]

Epidemiology