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ShimadaKMurayamaTYokodeMKitaTUzuiHUedaTet alN-acetylcysteine reduces the severity of atherosclerosis in apolipoprotein E-deficient mice by reducing superoxide production

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1.2.1 The main issue is optimization of drug bioavailability The main issue for any formulation of niclosamide (and indeed other BCS Class II and IV low water-solubility drugs) is how to optimize local bioavailability