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In addition, by reacting with oxidants such as superoxide anions, NO promotes cell injury and makes chondrocytes vulnerable to apoptosis induced by cytokines ( One study found that NO alone did not result in chondrocyte death but that NO triggered apoptosis when it reacted with O 2 - to produce chondrocytes (Nathan and Xie, 1994)

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The question worth asking is whether any of it is actually working

From the available evidence, only four clinical trials provided the necessary information for quantitative analysis, as they presented 2 2 tables with the number of AMS cases in each group according to LLS or equivalent criteria