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Approximately 20% of patients with primary ovarian insufficiency (POI) have been diagnosed with other autoimmune diseases, often thyroid, adrenal, and pancreatic diseases, and approximately 10% of patients with Addisons disease develop POI ( Figure 2 2.1.3 Iatrogenic factors Chemotherapy has multiple effects on ovarian function ( 2.1.4 Metabolic factors Ovarian function is decreased in patients with galactosemia, but the mechanisms responsible for this remain unclear

It stimulates your body to produce more growth hormone without raising cortisol or prolactin levels, making it a safe option for daily or long-term use

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