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doi: 10.3390/antiox11061085 252

Specifically, HMMER allows us to identify protein sequences encoding functional domains through implementing probabilistic Hidden Markov Models (HMM) to search for protein sequence homologs against a profile database such as Pfam

A reduced GSH status can further compromise the defense against oxidative stress and increase the oxidative modification of proteins or enzymes, causing major changes in the secondary structure that result in the impaired metabolic stability and function of modified proteins or enzymes [78,97]

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