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What is interesting about this study is the authors utilized the saliva cotinine level-verified continuous abstinence rate (CAR) at weeks 4 to 12 as their primary efficacy endpoint (cotinine is a metabolite of nicotine and can be measured in saliva, urine, or blood to detect the use of nicotine and/or tobacco)

Our parents and grandparents would have been imprisoned in their youth for using cannabis, while many of us in the modern age can use cannabis freely and legally

There are short and long-acting muscarinic receptor antagonists (SAMA and LAMAs)

A team of researchers including Roberta Freitas-Lemos, assistant professor at Virginia Techs Fralin Biomedical Research Institute at VTC, found that if menthol products were unavailable, smokers found replacement therapies such as nicotine gum and lozenges were practical alternatives, potentially improving health outcomes for people who use menthol cigarettes