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Autophagy and autophagy-related pathways in cancer

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Certain enzymes are highly expressed in diseased organs, while they are not expressed or expressed at relatively low levels in normal tissues 8,38,42

The traditional herbal medicine, HangAmDan-B (HAD-B), reduces LPS-induced NO and PGE2 production in macrophages by blocking ATF2 phosphorylation, consequently limiting tumor-promoting activity of TAMs in gastric and colorectal cancers (166)