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DOI: 10.1007/s11481-008-9121- Keywords MDMA (ecstasy, X, Molly) Drug Class: Drug of Abuse: CNS Stimulant & hallucinogen Street Names: Molly (for molecule), Mandy (in the UK), E, X, XTC Mechanism of Action: Similar mechanism as amphetamine, but with a preferential effect on SERT, and thereby strongly increases the extracellular concentration of serotonin

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G6PD-deficient cells are unable to generate enough NADPH under the condition of severe thiol depletion and GSH biosynthesis and methionine cycle are upregulated at the expense of ATP but fail to compensate for GSH depletion (311)

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