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While some degradation studies suggest longer stability windows, practical experience indicates noticeable potency loss beyond one month

Starting with lower doses and increasing gradually allows assessment of personal tolerance before committing to full therapeutic doses

Of note, the relative abundance of the Parasutterella genus, which was significantly enriched in both the vehicle- and 5A-1MQ-treated animals transitioned from WD to LD compared to both the WD and LD control groups, was observed to be significantly correlated (either positively or negatively) with 30 EWAT metabolites, both with and without outliers included