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With IV infusion therapy, treatment is usually less frequent: most patients come in one to two times per week over a series of weeks

Reviews in Cardiovascular Medicine, 25 (8), 297

doi: 10.1111/1750-3841.12221

Instead, our results suggest that the extensive interactions between the phosphorylated R-domain and the rest of Ycf1 represent a stimulatory R-domain architecture