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For SNVs, additional filters (ASRD 140 and CLPM = 0) in addition to the standard PASS filter

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Furthermore, you can also pull this method off with a regular pot and a sieve (yes, we love innovative improvisation here)

Once we had estimated the age attenuation factors, we carried out the last step, which consisted of adjusting the risk curve for the reference age group from step 1 using equation (1) to produce the age group-specific risk curves for each CVD outcome: We implemented the age adjustment at the draw level so that the uncertainty of the age attenuation factors could be naturally incorporated into the final adjusted age-specific RR curves