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For example, stromal cell-derived factor 1 alpha (SDF-1) doubled the recruitment of chondrogenic progenitor cells in a hyaluronate-fibrin hydrogel, which formed hyaline cartilage when cultured in a bovine cartilage explant model

Contrasting Preclinical Promise with Human Data The central challenge for clinicians is the stark contrast between the vast, overwhelmingly positive body of preclinical BPC-157 evidence and the near-total absence of published, peer-reviewed human clinical trials

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