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As such, additional investigations are highly warranted in order to further illustrate the potential benefits of the intra-articular delivery of antioxidants in diseased joints

In mouse models of highfat dietinduced liver steatosis, it significantly inhibits hepatic NNMT activity, reduces NAM methylation, increases NAD+ and SAM levels, enhances mitochondrial fatty acid oxidation, reduces hepatic triglyceride and lipid accumulation, lowers lipotoxicity markers (e.g., malondialdehyde, transaminases), improves hepatocellular injury, and reverses steatosis

Clinical Update 9/15/2023 Krill Oil for Knees