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Studies show that PPC supplementation can lower liver enzyme levels and improve ultrasound results in people with fatty liver disease in doses of 900-1,800mg/day.12 17 For general prevention, simply meeting the AI (425-550mg/day elemental choline) through diet or modest supplements is protective.1 Pregnancy & lactation Choline is critical for fetal brain development and a mothers milk supply.46 Most prenatals contain little or none, and over 90% of pregnant women fall short of the AI.1 40Experts advise aiming for 450-550mg/day, but one Cornell clinical trial showed that 930mg/day in late pregnancy produced infants with faster processing speeds than 480mg/day.1 47 Extra supplementation may be warranted

Previously, the Diagnostic Statistical Manual (DSM) Version IV Text Revision divided ASD into several diagnoses including autistic disorder, Asperger syndrome, and pervasive developmental disorder-not otherwise specified

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PMID 16856044