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Outcome measures include neurological severity scoring, rotarod and beam walk performance, histological assessment of lesion volume, and immunohistochemistry for axonal markers and myelin basic protein

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No significant metabolic contraindications: Active malignancy, uncontrolled insulin resistance, or significant thyroid disease can alter both the risk-benefit calculation and the expected response

Community sources describe this as the most common failure mode for ultra-low-cost marketplace listings the ones priced at $3-5 per 30 mL vial, well below the cost floor for USP-compliant product