In this process, depletion of large Fe-S clusters disrupts the electron transport chain, while the blockage of the tricarboxylic acid cycle further impairs mitochondrial energy metabolism, ultimately leading to cell death through proteotoxic stress and metabolic disruption (173)
Ten studies used a dosage of less than 500 mg, seven trials used 500 to 1,000 mg, 12 used 1,000 to 2,000 mg, and 13 used 2,000 or more mg.20 A 2019 systematic review and meta-analysis of 13 randomized clinical trials found that L-carnitine supplementation was significantly associated with lower levels of C-reactive protein in comparison to controls
One thing you can do is make sure that the product is certified by NSF International, which independently tests and certifies dietary supplements and nutritional products, and ensures that they dont contain undeclared ingredients or contaminants
Eur J pharmaceutics biopharmaceutics