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While vitamin B12 injections are predominantly safe, some individuals might experience side effects such as: Mild diarrhea Itching, rash, or redness at the injection site Headache, dizziness, nausea, or vomiting Swelling sensation, cough, or shortness of breath Chest tightness, rapid heartbeat, or blood clots (rare) Severe side effects, although infrequent, require immediate medical attention

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After reconstitution, the vial must be stored in a refrigerator (not frozen) at a temperature between 36F and 46F (2C and 8C)