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Johnson et al., 2020 examined the alteration in the gene expression leading by YB-1 knockdown in the three mesothelioma cell lines, they utilized an unbiased RNA-seq method (REN, VMC23 and MSTO-211H cells)
Together, these changes mark a structural shift
The advice part is given in the piece of discourse presented in the top line of text: Go to grad school, they said, complemented by the positive stance expressed by the same unidentified them in the bottom line of text: It will be fun, they said. Combining this with the negative emotional stance prompted by the picture of the inconsolably crying man leads viewers to pragmatically infer a scenario where the advice was followed, but led to bitter disappointment
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