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As both play very important roles in the immune response, and the status or availability of one has been shown to directly affect the other, it is likely that deficiency of either can have a direct effect on the severity of COVID-19 as well as many other diseases therefore, taking steps to ensure adequate levels of both is essential to better health

Increased CETP activity was noted in individuals with type 1 diabetes, resulting in peripheral hyperinsulinaemia [29]

Reactive oxygen species (ROS) levels were measured with lucigenin-enhanced chemiluminescence method as previously described 29

doi: 10.1038/nrd1175 101 ChurchLDMcDermottMF