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While the mechanism is not fully understood, the theory involves sustained hormonal stimulation of pancreatic cells potentially triggering inflammatory cascades in susceptible individuals

Pernicious anaemia (an autoimmune condition affecting B12 absorption) is a common cause of B12 deficiency that requires specific testing for anti-intrinsic factor antibodies

Personalized supplementation might include optimization of dose, timing and natural agents combinations according to tumour molecular signature, patient immune status and lifestyle habits by integrating traditional oncology with precision nutraceutical medicine (249)

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