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However, recent data indicate that BAG3-independent autophagic pathways cannot fully compensate for CASA deficiency and may even worsen the proteostatic imbalance

The Approach Instead of immediately relying on topical steroids, we took a more comprehensive approach

The most common side effects are mild and may include temporary pain, redness, or swelling at the injection site

The program involved locating and replacing between 64,000 and 84,000 customer-owned lead service lines usually found in Denver-area homes built before 1951, distributing more than 100,000 pitchers and water filters certified to remove lead from drinking water and launching a major public health education program