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More recently, glutathione-based chemical peel has also gained popularity.[] GLUTATHIONE AS A MESOTHERAPY Though there is lack of literature regarding the efficacy and methodology of use of glutathione as mesotherapy solution, it is widely being practiced by the dermatologists for treatment of melasma either as monotherapy or along with ascorbic acid, pyruvic acid, vitamin E, etc.[] TRANSDERMAL DELIVERY To enhance the permeability and reduce the foul odor associated with the topical applications of glutathione, Lee et al

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The temperature applied in this study was initially reduced at a programmed rate of 5C/min from 4C to 10C, then at a programmed rate of 40C/min from 10 to 100C and finally at a programmed rate of 20C/min from 100 to 140C

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