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Moreover, chronic administration burdens (daily pills or injections for years) reduce compliance, especially in neurodegenerative conditions where cognitive impairment or motor deficits exist

Medium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trial

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Diarrhea and constipation are also frequent, with each affecting 10 to 20 percent of individuals